When characters run - as I said - you can pose them realistically or you can pose them "cartoon-ily." I happen to prefer the cartoon option because it looks funny. Realistic poses, irrespective of the amount of skill required - and that requires some real skill - don't look especially funny.
Now H-B used to make their funny characters run straight up and down, arms hanging at their sides. To me, the effect was hilarious. This is from a Top Cat model sheet:
|Top Cat running for his life... but notice he doesn't lean into the run. He runs straight up and down.|
So there's Top Cat out for a run. He's not jogging, that's for sure. He's upset about something and anxious. But he runs straight up and down. Whatta geek! Now that's funny! Look at the little black spot underneath him: the suggestion of a shadow. Meaning he's airborne for #$%^& sake and he's still running straight up and down. C'mon, Top, lean into it!!
Next sesh we're still into running, but I found a poster that puts a little variation into TC's pose. Equally as unlikely and equally as funny. Stay tuned.